Taita Isaías Muñoz Macanilla, an Indigenous activist and traditional doctor, prepares for an ayahuasca ceremony in Barcelona, highlighting the growing trend of ayahuasca retreats in Europe, particularly in Spain and Portugal. These retreats offer a blend of traditional practices and modern wellness approaches, attracting Europeans seeking spiritual experiences. However, concerns about safety and cultural appropriation arise as these retreats adapt Indigenous rituals for Western participants. The legal status of ayahuasca in these countries is ambiguous, allowing for its use in a permissive environment, though this situation is precarious.