A major review published in Nature Reviews Cardiology reveals that all nicotine-containing products, including e-cigarettes and nicotine pouches, are harmful to cardiovascular health. The study highlights a 'cardiovascular continuum of harm' where traditional cigarettes are the most dangerous, but even smoke-free alternatives still pose risks. Researchers emphasize that the only way to eliminate nicotine-related cardiovascular risks is complete abstinence from nicotine.